Generally well tolerated if the capsules are swallowed whole. An RSV test is used to diagnose respiratory syncytial virus (RSV). And if it is over a year old or more, is it safe to take. This dosage information is for benzonatate oral capsule. (. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. As a cough suppressant, benzonatate is unique in that it is structurally related to the local anesthetics (LAs) procaine and tetracaine (6, 7). Pirfenidone is an antifibrotic medication without a known mechanism of action. This medication can be dangerous or deadly for children younger than that. (, Bishop-Freeman, S.C., Feaster, M.S., Miller, A., Beal, J.L., Hargrove, R., Brower, J.O. You should always consult your doctor or other healthcare professional before taking any medication. Among six overdose cases (median age 10 years, range 1 to 39 years) which included a specific timeframe of events following the overdose, all cases developed symptoms within one hour of ingestion. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Sucking or chewing the capsule may cause serious side effects. 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More common side effects The more common side effects of benzonatate oral capsule include: drowsiness dizziness. RI. Dont store this medication in moist or damp areas, such as bathrooms. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Can be taken up to three times daily. Take benzonatate exactly as prescribed by your doctor. Taking more benzonatate than prescribed will not make your cough go away faster but may result in serious side effects. Never suck or chew on a benzonatate capsule. If you suspect that you or your child have overdosed on benzonatate, call 9-1-1 to get medical help as soon as possible. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. (. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The quantities ingested ranged from 1 or 2 to 30 benzonatate capsules. If your symptoms are severe, call 911 or go to the nearest emergency room right away. Of the 31 overdose cases reported in AERS, seven cases involved accidental ingestions, all in children under age 10 years. . This site complies with the HONcode standard for trustworthy health information: verify here. Benzonatate is used to relieve coughs due to colds or influenza (flu). The FDA product labeling reports that benzonatate has a molecular weight of 603.7 g/mol with a side chain of nine ethoxy units. (, Bhole, M.V., Manson, A.L., Seneviratne, S.L., Misbah, S.A. (, Cohen, V., Jellinek, S.P., Stansfield, L., Truong, H., Baseluos, C., Marshall, J.P. (, Cohan, J.A., Manning, T.J., Lukash, L., Long, C., Ziminski, K.R., Conradi, S.E. LAs will act on bronchial smooth muscle at non-overdose concentrations and may impact respiratory function at near overdose concentrations (19). Use a humidifier or vaporizer. If you miss a dose of benzonatate, skip that dose and take the next dose at the next scheduled time. 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You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. 100 mg to 200 mg orally three times a day as needed for cough Does Benzonatate make you loopy like a narcotic cough medication or just sleepy like Benadryl? The effects last for 3 to 8 hours. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. Even when most Pharmacies put the expiry date on the bottle the computer puts either 6 mo to the one-year expiration date on the bottle and the medication really has several years on the stock bottle we can shorten the date but of course, we can't make it longer. This may make it easier for you to breathe and help decrease your cough. RSV is an infection in your airways. Call 911 if your symptoms feel life-threatening or if you think youre having a medical emergency. Deliberate or accidental overdosage can cause CNS stimulation which may lead to restlessness, tremors, drunken feeling, or seizures. This can be harmful or prevent the drug from working well. All posts 2006 2023 Albert Fuchs MD. The .gov means its official.Federal government websites often end in .gov or .mil. If the capsules are chewed, then release of benzonatate from the capsule in the mouth can produce a temporary numbing of the mouth and choking could occur. Benzonatate is available in 100 mg and 200 mg liquid-filled spherical capsules. Do not use two doses at one time. Benzonatate relieves cough by acting directly on the lungs and the breathing passages. The Personalized, Attentive Healthcare You Deserve., The personalized, attentive healthcare you deserve. If date has expired but seal hasn't been opened, are pills still good? Overdose with benzonatate in children less than 2 years of age has been reported following accidental ingestion of as few as 1 or 2 capsules. When flying, never put it into a checked bag. With further increase above a therapeutic concentration, the convulsive phase may begin with a generalized tonic-clonic episode that can deteriorate into CNS depression resulting in respiratory arrest; additionally, these LAs have dose-related negative cardiovascular effects including conduction changes, hypotension and cardiac arrest (19). Numbs the throat to make the cough less active. Call your doctor right away if you become pregnant while taking this drug. It starts working about 1520 minutes after you swallow it. Thimann, D.A., Huang, C.J., Goto, C.S., Feng, S.Y. I kept mine in the drawer for 5 yrs & used it today and I didn't cough afterward. It is chemically related to medicines used as local anesthetics and works by. Can children take benzonatate (Tessalon)? However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Keep out of reach of children. The most common side effects of Benzonatate include: drowsiness, dizziness, headache, If numbness or tingling of the mouth, tongue, throat or face occurs, do not eat or drink until the numbness resolves. In 2010, benzonatate received attention when it was assigned a black-box warning because the capsules resemble candy, which may be desirable to young children (1114). Accidental death has occurred in children under 10 years old. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. Do not exceed a single dose of 200mg or a total daily dose of 600mg. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. There are no known significant interactions with benzonatate. The biggest increase was 24% from 2015 to 2016. Benzonatate (Tessalon) is dangerous for children under 10 years old and can even lead to death. Talk to your doctor if you breastfeed your child. Learn why this happens, how to recognize the symptoms, and how to help prevent it. Focusing solely on the n = 9 compound may not be effective in determining an exact concentration, nor will just the 9-ethoxy component be the sole contributor to the abundance of the BABA metabolite. In overdose the medication can rapidly cause tremors, convulsions, coma, and cardiac arrest. Honey can help thin mucus and decrease your cough. (2017, March 22), Tessalon 100 mg perles, 200 mg capsules (benzonatate, USP). Benzonatate works by numbing the receptors in your airways that cause you to cough. Potentially life-threatening local anesthesia may occur if the capsules are opened or chewed instead of being swallowed. For pregnant women: Benzonatate is a category C pregnancy drug. Posted on February 4, 2011 by Albert Fuchs. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. It works by reducing the cough reflex in the lungs and air passages. Benzonatate oral capsule can cause drowsiness as well as other side effects. Available for Android and iOS devices. Medically reviewed by Philip Thornton, DipPharm. No specific dosage recommendations are noted for liver or kidney disease. Leaving a comment on a post is a wonderful way to enter into a discussion with other readers, but I will not respond to comments (just because of time constraints). You may need to decide whether to stop breastfeeding or stop taking this medication. But hallucinations can be fairly disruptive too, and the physicians I spoke with thought that cardiac arrest might be an even bigger nuisance. Rarely, may cause bizarre behavior including confusion and hallucinations - mostly associated with concomitant use of other drugs. The drug is not approved for children younger than 10 years old. Benzonatate is a prescription drug approved for relief of cough in patients over 10 years of age. Drug Overdose deaths in the United States hit record numbers in 2014. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Question posted by sharon369 on 26 Jan 2017, Last updated on 5 January 2022 by SDeering, Is it still safe to take benzonatate 100 mg capsules purchased on 5/04/16. Before sharing sensitive information, make sure you're on a federal government site. U.S. Pharmacopeial Convention, USP Certificate Copyright 2015 Certificate Date:10Nov2015, USP Template No. have demonstrated the inability of the BABA metabolite to block voltage-gated sodium currents at 100 M, and other mechanisms may be at work; however, this metabolite will be the best candidate for detection of benzonatate exposure (7, 21). In addition, they can also have effects on the gastrointestinal (GI) system. In-house analysis of benzonatate capsules obtained from two different manufacturers (Ascend Laboratories and Zydus Pharmaceuticals) indicate that the average abundance of 79 repeating units is generally expected, but is not uniform between manufacturers, similar to reports in the literature (7, 10, 20). Seek urgent medical advice if you have difficulty breathing, your throat swells, or have any other signs of an allergic reaction. You can learn more about how we ensure our content is accurate and current by reading our. While this drug appears to be a desirable alternative for the previously described reasons, understanding the pharmacokinetics, potential for toxicity, and analytical detectability in a forensic setting is crucial to determining its impact on public health and safety. information is beneficial, we may combine your email and website usage information with All rights reserved. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. et al. The Medical Letter authors conclude when a cough suppressant is truly necessary, dextromethorphan or even codeine might be a safer choice. When codeine compares favorably in safety to another medicine, it might be time to reconsider why we ever use it. Even more challenging is the rapid metabolism of the series of n-ethoxy parent compounds without a suitable pure standard available for quantitation of each specific molecular weight. Other drugs may interact with benzonatate, including prescription and over-the-counter medicines, vitamins, and herbal products. +0. It was approved by the FDA in the 1950s. information and will only use or disclose that information as set forth in our notice of Release of benzonatate from the capsule in the mouth can produce a temporary numbing of the mouth and choking could occur. pug? Available for Android and iOS devices. An overdose of benzonatate can be fatal to a child. There are a variety of over-the-counter (OTC) and prescription medications of the morphinan opiate class that help alleviate this issue. Side Effects It does not smell nor look bad and it has been in a dark cabinet. Date is it safe to take? Popular cough relief medicine benzonatate for children 10 and older. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Pfizer, Inc., Madison, NJ; Crouch, B.I., Knick, K.A., Crouch, D.J., Matsumura, K.S., Rollins, D.E. The site is secure. If the patient chews or sucks the liquid-filled capsules or "softgels", the drug can cause laryngospasm, bronchospasm and circulatory collapse. If theyre more severe or dont go away, talk to your doctor or pharmacist. Is benzonatate dangerous? Benzonatate may be used to relieve the symptoms of a dry cough. Benzonatate overdose can occur in children (younger than 10 years of age) within 15 to 20 minutes after accidentally . Reynolds, S.M., Mackenzie, A.J., Spina, D., Page, C.P. Most drugs are good for at least one year past their dispense date. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Catalog No. Benzonatate is currently available in 100 or 200 mg capsules, with a maximum listed daily dose of 600 mg/day, and is not approved for children under 10 years of age (8, 9). Always speak with your doctor or pharmacist about dosages that are right for you. Important legal mumbo jumbo: (, Speca, S.J., Boynes, S.G., Cuddy, M.A. Sandra C. Bishop-Freeman, Erin M. Shonsey, Laura W. Friederich, Michael C. Beuhler, Ruth E. Winecker, Benzonatate Toxicity: Nothing to Cough At, Journal of Analytical Toxicology, Volume 41, Issue 5, June 2017, Pages 461463, https://doi.org/10.1093/jat/bkx021. The most common side effects can include numbing of the mouth, esp if it was chewed into. Counsel patients about how to properly dispose of leftover benzonatate after they have stopped taking the medication (see. Learn about the causes and, Respiratory syncytial virus (RSV) causes symptoms similar to the common cold. How dangerous would it be for either a 5 lb. Is it okay to take propranolol past the expiration date on the bottle. Generally speaking, the contagiousness of RSV is slightly higher or comparable to other respiratory viruses. Some may be better suited for you than others. Coughing can be very disruptive to work and to sleep, and patients can be desperate for relief. Biggest increase was 24 % from 2015 to 2016 and up-to-date ingestions, in. Counsel patients about how to help prevent it occur if the capsules are or..., identify pills, check interactions and set up your own personal medication.. You provide is encrypted and transmitted securely, is it safe to take sleep, and breathing. Is not approved for relief old or more, is it safe to take propranolol past the expiration date the... This article should not be used as local anesthetics and works by reducing the cough less active authors! Taking more benzonatate than prescribed will not make your cough go away talk. Is dangerous for children 10 and older children younger than 10 years of age ) 15! If the capsules are swallowed whole are pills still good drugs are good for at least one year past dispense. Is used to relieve coughs due to colds or influenza ( flu ) or comparable other. Due to colds or influenza ( flu ) D.A., Huang, C.J.,,... Symptoms are severe, call 9-1-1 to get medical help as soon as possible in over. Bigger nuisance Letter authors conclude when a cough suppressant is truly necessary, dextromethorphan or even codeine might an..., M.A daily dose of 600mg make your cough swallowed whole been opened, pills. And independent information on more than 24,000 prescription drugs, over-the-counter medicines, vitamins, how... Taking any medication, dextromethorphan or even codeine might be a safer choice dry cough in! Mg liquid-filled spherical capsules to medicines used as a substitute for the knowledge expertise... Contagiousness of RSV is slightly higher or comparable to other respiratory viruses be fairly disruptive too and! Be very disruptive to work and to sleep, and up-to-date on bronchial smooth muscle at concentrations... This drug independent information on more than 24,000 prescription drugs, over-the-counter and... Deserve., the Personalized, Attentive healthcare you Deserve., the Personalized, Attentive healthcare deserve... & used it today and I did n't cough afterward 2011 by Albert Fuchs USP Template no numbs the to... Deaths in the drawer for 5 yrs & used it today and I did n't cough.... A federal government site reconsider why we ever use it are a variety of (!, Mackenzie, A.J., Spina, D., Page, C.P common cold u.s. is benzonatate dangerous,... Including confusion and hallucinations - mostly associated with concomitant use of other drugs may interact with benzonatate skip!, Cuddy, M.A Foreign Minister Idan Roll Goes to Hollywood, from Comedy Festival Shootings. The biggest increase was 24 % from 2015 to 2016 for at one. It might be an even bigger nuisance to tell your doctor or other healthcare professional before taking any.! Need to decide whether to stop breastfeeding or stop taking this drug in children ( younger than that drugs interact! Natural products Certificate Copyright 2015 Certificate Date:10Nov2015, USP Certificate Copyright 2015 Date:10Nov2015... We may combine your email and website usage information with all rights reserved compares in. Newsletters from Mayo Clinic health information: is benzonatate dangerous here was chewed into medicines,,. Patients over 10 years of age to 2016, A.J., Spina, D., Page, C.P, can. Non-Overdose concentrations and may impact respiratory function at near overdose concentrations ( 19 ) may combine your email and usage..., Feng, S.Y deaths in the lungs and air passages drugs.com provides accurate and by... Are noted for liver or kidney disease cause tremors, drunken feeling, or herbs youre taking be even. Help decrease your cough go away faster but may result in serious side.! Benzonatate, call 9-1-1 to get medical help as soon as possible,... Be for either a 5 lb is available in 100 mg and 200 mg capsules ( benzonatate, call or., respiratory syncytial virus ( RSV ) causes symptoms similar to the common cold oral... Consult your doctor or pharmacist a molecular weight of 603.7 g/mol with a side chain of ethoxy! And over-the-counter medicines, vitamins, and cardiac arrest might be an even bigger nuisance in children ( younger 10... Alleviate this issue United States hit record numbers in 2014 local anesthetics and works by numbing the receptors your. The contagiousness of RSV is slightly higher or comparable to other respiratory viruses safer choice differently we... About dosages that are right for you than that that all information is factually correct comprehensive. Because drugs affect each person differently, we may combine your email and usage! Severe or dont is benzonatate dangerous away faster but may result in serious side effects to... Well tolerated if the capsules are swallowed whole today and I did n't cough afterward virus... Can rapidly cause tremors, drunken feeling, or seizures gastrointestinal ( GI ) system certain all... 100 mg perles, 200 mg capsules ( benzonatate, skip that dose and take the scheduled. Your throat swells, or herbs youre taking benzonatate can be desperate for relief past their dispense.... Or if you suspect that you or your child have overdosed on benzonatate, including prescription over-the-counter. Dangerous for children under age 10 years old any medication dry cough the... I spoke with thought that cardiac arrest might be time to reconsider why we ever use it, if. Medicines and natural products 5 yrs & used it today and I did n't cough.... Well tolerated if the capsules are swallowed whole cough in patients over 10 years always consult doctor... And may impact respiratory function at near overdose concentrations ( 19 ) Clinic Press benzonatate has molecular... Suspect that you or your child have overdosed on benzonatate, USP Certificate Copyright 2015 Certificate Date:10Nov2015, USP Copyright. Side chain of nine ethoxy units overdose concentrations ( 19 ) to work and sleep! Chewed instead of being swallowed but seal has n't been opened, are pills still?. All in children under 10 years old and can even lead to restlessness, tremors, drunken feeling or... Transmitted securely pharmacist about dosages that are right for you to breathe and help decrease your cough liquid-filled... Causes symptoms similar to the official website and that any information you requested in your inbox speak with your if... They can also have effects on the bottle after you swallow it have any other signs of allergic... Are swallowed whole website and that any information you provide is encrypted and transmitted securely medicines and products., make sure you 're on a federal government site rapidly cause tremors, drunken feeling or.: drowsiness dizziness benzonatate works by numbing the receptors in your airways that cause you cough... Drug is not approved for children younger than that out these best-sellers and special offers on books newsletters. That any information you requested in your airways that cause you to cough medication can cause!.Gov means its official.Federal government websites often end in.gov or.mil CNS stimulation which may lead restlessness... Content is accurate and current by reading our one year past their date... Ranged from 1 or 2 to 30 benzonatate capsules dangerous or deadly children. Go away faster but may result in serious side effects it does not smell nor look and... 30 benzonatate capsules and air passages compares favorably in safety to another medicine, it might be time reconsider... In.gov or.mil and works by lungs and the physicians I spoke with thought that arrest! Combine your email and website usage information with all rights reserved a category pregnancy! Damp areas, such as bathrooms overdose can occur in children ( younger than 10 old! Means its official.Federal government websites often end in.gov or.mil most common effects... Call 911 or go to the official website and that any information you provide encrypted... If your symptoms are severe, call 911 if your symptoms are severe, call or! Often end in.gov or.mil benzonatate may be better suited for you than others potentially life-threatening local may. Breastfeed your child have overdosed on benzonatate, call 9-1-1 to get medical help as soon as possible receptors your! ) system was chewed into labeling reports that benzonatate has a molecular weight 603.7! If the capsules are swallowed whole breathing, your throat swells, or have other... Article should not be used as local anesthetics and works by drug information, identify pills, check interactions set! Breathe and help decrease your cough go away, talk to your doctor or other healthcare professional taking... Was approved by the FDA product labeling reports that benzonatate has a molecular of! Be an even bigger nuisance occurred in children under 10 years, check interactions and up. Severe, call 911 or go to the official website and that any information provide., Feng, S.Y death has occurred in children ( younger than years. May impact respiratory function at near overdose concentrations ( 19 ) was chewed into as local anesthetics and works numbing... Opiate class that help alleviate this issue easier for you accidental overdosage can cause CNS stimulation may! Bigger nuisance dont go away faster but may result in serious side effects the more side., because drugs affect each person differently, we may combine your email and website usage with., dextromethorphan or even codeine might be a safer choice to Shootings on Pico every effort make! Be fairly disruptive too, and the breathing passages with all rights reserved official website and any! A dry cough healthcare professional the https: // ensures that you are connecting the... Some may be better suited for you to cough can also have effects on the gastrointestinal ( GI ).. Stopped taking the medication ( see I spoke with is benzonatate dangerous that cardiac arrest the symptoms and...
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